Faculty

Xunbin WEI

Biography

Xunbin Wei is the Professor of biomedical engineering. His major research interests include cancer detection by optical means, and optical manipulation of living biological cells. He has been working in the areas of monitoring circulating tumor cells and cancer metastasis in live animals, optical manipulation of biological cells both in vitro and in live animals, as well as developing fluorescence dyes for tumor imaging. For 20 years, he has devoted efforts to the development of an effective method, “In Vivo Flow Cytometry”, for the in vivo detection of circulating tumor cells in metastatic tumors. His work on in vivo flow cytometer was well documented in thirty publications. Specifically, it is reflected by a publication in Cancer Research, where his work was commented as “In vivo flow cytometry may offer a breakthrough technology to elucidate mechanisms of hematogenousmetastasis and to monitor the efficacy of cancer therapy”.

Dr. Wei also pioneered in the development of an optical-trap-based single-cell assay to study T lymphocyte activation. More importantly, Dr. Wei has recently used infrared optical tweezers to trap and manipulate red blood cells within subdermal capillaries in living mice, which has not been achieved so far (Nature Communications). In addition, He has contributed to the development of near-infrared fluorescence probes for cancer detection.  His work on fluorescence nanoprobes for tumor imaging has resulted in more than 10 publications, including ACS Nano and AFM.

Dr. Wei holds an AB from University of Science & Technology, China, and a PhD in Physiology and Biophysics from University of California, Irvine. He received the Chinese National Outstanding Young Scientist Award. He is a fellow of the international society for optical engineering (SPIE). Dr. Wei is the Associate Editor of Cytometry Part A (since 2014). He is also the President-Elect of Chinese Association of Biomedical Optics (2015-present). He is also the vice chair of Chinese Association of Laser Medicine (2006-present).

Education background

1988-2003 Bachelor - University of Science & Technology, China

1993-1999 Ph.D. - University of California, Irvine

Work Experience

2001-2005 Instructor in Dermatology, Harvard Medical School

2005-2010   Professor, Fudan University, Shanghai, China

2011-       Distinguished Professor, Shanghai Jiao Tong University

Areas of Research Interests

Biomedical Optical Imaging and detection

Boards, Advisory Committees, Professional Organizations
Selected Publications
Patents