Junfeng SUN

Associate professor

Email : jfsun@sjtu.edu.cn

Office address : 211 Med-X Research Institute (Xuhui)


Dr. Junfeng Sun is the Tenured Associate Professor of biomedical engineering at School of Biomedical Engineering, Shanghai Jiao Tong University. His research interests include neuromodulation techniques, neuroimaging analysis, and their applications. He observed the neuroprotective effects of transcranial ultrasound stimulation (TUS) preconditioning for subsequent focal cerebral ischemia in rats and the antidepressant effects of TUS in rats. He has developed integrated TUS system and real time TUS navigation system based on optical tracking, and are working for the applications of TUS on depression and other mental disorders. He also performs EEG/neuroimaging data analysis, develops EEG/neuroimaging based individualized transcranial magnetic stimulation, and applies them to investigate cognitive function and brain abnormalities in mental disorders (e.g., depression, schizophrenia), stroke, dementia, and Parkinson's disease. 

He has published more than 50 refereed papers in SCI journals such as NeuroImage, Brain Stimulation, IEEE Transactions on Biomedical Engineering, IEEE Transactions on Neural Systems & Rehabilitation Engineering, Signal Processing, Neurophotonics, Biological Psychology, and Scientific Reports. He has gotten grants from National Natural Science Foundation of China (PI), National Key R&D Program of China (Co-PI), National Basic Research Program of China (Co-PI), Natural Science Foundation of Shanghai, China (PI), and Science and Technology Commission of Shanghai Municipality, China (PI). He is IEEE Senior Member (2015-), Associate Editor of Medical and Biological Engineering and Computing (2018-), Academic Editor of BioMed Research International (2020-), Associate Editor of Frontiers in Neuroergonomics (2020-), Chair of Local Organizing Committee for 2017 IEEE EMBS Neural Engineering Conference (NER’17), Session Chair for the session Brain Functional Imaging I of IEEE EMBC 2017, Session Chair for the session Brain Therapy of 17th International Symposium on Therapeutic Ultrasound, reviewers for more than 30 international journals, reviewer for Grant Proposal for National Natural Science Foundation of China (NSFC).

He instructs the undergraduate course Biomedical Signals and Systems (I) and the graduate course Biomedical Signal Processing, provides supervision for Ph.D. students and MS students, and acts as advisor/tutor for undergraduate students.

Education background

1998-2002 Bachelor (Electronic Sci.&Info. Systems)– Nanjing University

2002-2005 Master (Acoustics) – Nanjing University

2005-2009 Ph.D. – The Hong Kong Polytechnic University 

Work Experience

Jan 2020 – present, Tenured Associate Professor, School of Biomedical Engineering, Shanghai Jiao Tong University

Jan 2014 – Dec 2019, Associate Professor (Tenure-Track), SJTU Distinguished Research Fellow, School of Biomedical Engineering, Shanghai Jiao Tong University

Aug 2012 – Aug 2013, Visiting Scholar, Department of Biomedical Engineering, University of Minnesota, USA

May 2011 – Dec 2013, Research Assistant Professor, School of Biomedical Engineering, Shanghai Jiao Tong University

Mar 2009 – Dec 2013, Research Assistant Professor, Med-X Research Institute, Shanghai Jiao Tong University

Jan 2009 – Mar 2009, Research Associate, The Hong Kong Polytechnic University

Areas of Research Interests

Transcranial Ultrasound Stimulation and Transcranial Magnetic Stimulation, Neuroimaging Analysis (EEG, fMRI, etc), Brain Network Modelling, and Applications of these techniques to Cognitive Function and Intervention for Depression, Schizophrenia, Stroke, Aging and other Mental Disorders.  

Honors And Awards

SMC-Morning Star Award for Junior Investigator (2011), Shanghai Jiao Tong University, Shanghai

Boards, Advisory Committees, Professional Organizations

Senior Member, IEEE (2015 - present)

Associate Editor, Medical and Biological Engineering and Computing (2018-)

Academic Editor, BioMed Research International (2020-)

Associate Editor, Frontiers in Neuroergonomics (2020-)

Guest Editor, BMC Neuroscience (2017-) for special theme: Transcranial Ultrasound Stimulation and its Applications in Neuroscience

Guest Associate Editor (2015-), Leading Topic Editors for research topic: Brain Networks in Aging: Reorganization and Modulation by Interventions, Frontiers in Aging Neuroscience

Chair of Local Organizing Committee, 2017 IEEE EMBS Neural Engineering Conference (NER’17)

Session Co-Chair, Brain Functional Imaging I, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’17), 2017, Jeju, Korea.

Session Co-Chair, Brain Therapy, 17th International Symposium on Therapeutic Ultrasound, 2017, Nanjing, China.


Biomedical Signals and Systems-1 - BM251, 32/32 hours, Spring, Undergraduate courses

Biomedical Signal Processing, X082008, 39/48 hours, Autumn, Graduate courses

Research Projects

1. Study on the Techniques and Mechanisms of Individualized Transcranial Magnetic Stimulation for Schizophrenia Patients based on Longitudinal Neuroimaging, National Natural Science Foundation of China (NSFC), 01/01/2020–30/12/2023, PI

2. Research and Development of Transcranial Ultrasound Stimulation System with infrared optical navigation, Science and Technology Commission of Shanghai Municipality (STCSM), 01/04/2019–31/03/2022, PI

3. Study on the Effects of Ageing on Visual-spatial Attention and Attention-related Networks Based on Functional Magnetic Resonance Imaging, National Natural Science Foundation of China (NSFC), 01/01/2017–30/12/2020, PI

4. Study on the Dynamics and Controllability of Brain Networks Based on Neuroimaging Information, Natural Science Foundation of Shanghai, 01/07/2016–30/06/2019, PI

5. Study on Cross-modal Neuroimaging Biomarkers for Diagnosis and Treatment of Schizophrenia and Bipolar Disorder, National Key R&D Program of China, 07/2017–12/2019, Co-PI

Selected Publications

1. Jing Du, Hong Zhu, Jie Zhou, Peiwen Lu, Yage Qiu, Ling Yu, Wenwei Cao, Nan Zhi, Jie Yang, Qun Xu*, Junfeng Sun*, Yan Zhou*, Structural Brain Network Disruption at Preclinical Stage of Cognitive Impairment Due to Cerebral Small Vessel Disease, Neuroscience, 449: 99–115, 2020 (*Corresponding author) 

2. Nishuai Yu, Jun Cai*, Xuanyue Xu, Yining Yang, Junfeng Sun*, Masking effects on subjective annoyance to aircraft flyover noise: An fMRI study, Human Brain Mapping, 41: 3284-3294, 2020. (*Corresponding author) 

3. Wen Jin, Hong Zhu, Pin Shu, Shanbao Tong, Junfeng Sun*, Extracting individual neural fingerprint encoded in functional connectivity by silencing indirect effects, IEEE Transactions on Biomedical Engineering, 67(8): 2253-2265, 2020. (*Corresponding author) 

4. Lifu Deng, Yan Cheng, Xinyi Cao, Wei Feng, Hong Zhu, Lijuan Jiang, Wenyuan Wu, Shanbao Tong, Junfeng Sun*, Chunbo Li*, The effect of cognitive training on the brain’s local connectivity organization in healthy older adults, Scientific Reports, 9:9033, 2019. (*Corresponding author)  

5. Daqu Zhang, Hangdao Li, Junfeng Sun, Weiwei Hu, Wen Jin, Shengtian Li, and Shanbao Tong, Antidepressant-like effect of low-intensity transcranial ultrasound stimulation, IEEE Transactions on Biomedical Engineering, 66(2): 411-420, 2019. 

6. Qingyu Zeng, Shibin Hong, Xue Wang, Yirui Cheng, Junfeng Sun*, Weiliang Xia*, Regulation of exosomes secretion by low-intensity pulsed ultrasound in lung cancer cells, Experimental Cell Research, 383: 111448, 2019. (*Corresponding author) 

7. Qiangfeng Zhao, Xiong Jiao, Yingying Tang, Shan Chen, Shanbao Tong, Jijun Wang*, Junfeng Sun*, Temporal Characteristics of Attentional Disengagement from Emotional Facial Cues in Depression, Neurophysiologie Clinique/ Clinical Neurophysiology, 49: 235-242, 2019.(*Corresponding author) 

8. Adrian Curtin, Hasan Ayaz, Yingying Tang, Junfeng Sun, Jijun Wang, Shanbao Tong, Enhancing neural efficiency of cognitive processing speed via training and neurostimulation: An fNIRS and TMS study, Neuroimage, 198: 73–82, 2019. 

9. Yingying Tang, Chunwei Ying, Junjie Wang, Xiong Jiao, Zhenying Qian, Tianhong Zhang, Shanbao Tong, Jianhua Sheng, Junfeng Sun*, and Jijun Wang*, “Precise theta burst transcranial magnetic stimulation selectively reduced duration-related mismatch negativity”, Biological Psychology, 137: 125-132, 2018. (*Corresponding author)  

10. Adrian Curtin, Junfeng Sun, Hasan Ayaz, Zhenying Qian, Banu Onaral, Jijun Wang, and Shanbao Tong, Evaluation of evoked responses to pulse-matched high frequency and intermittent theta burst transcranial magnetic stimulation using simultaneous functional near-infrared spectroscopy, Neurophotonics, 4(4): 041405, 2017.  

11. Hangdao Li, Junfeng Sun, Daqu Zhang, Daryl Omire-Mayor, Peter A. Lewin, Shanbao Tong, “Low-intensity (400 mWcm2, 500 kHz) pulsed transcranial ultrasound preconditioning may mitigate focal cerebral ischemia in rats”, Brain Stimulation, 10: 695-702, 2017.  

12. Lifu Deng, Junfeng Sun*, Lin Cheng, and Shanbao Tong, “Characterizing dynamic local functional connectivity in the human brain”, Scientific Reports, 6: 26976, 2016. (*Corresponding author)  

13. Qiangfeng Zhao, Yingying Tang, Shan Chen, Yuanyuan Lyu, Adrian Curtin, Jijun Wang, Junfeng Sun*, Shanbao Tong*, Early perceptual anomaly of negative facial expression in depression: An event related potential study, Neurophysiologie Clinique/ Clinical Neurophysiology, 45: 435-443, 2015. (*Corresponding author) 

14. Xiangfei Hong, Junfeng Sun, Jesse Bengson, George Mangun, and Shanbao Tong, “Normal aging selectively diminishes alpha lateralization in visual spatial attention”, Neuroimage, 106: 353-363, 2015. 

15. Junfeng Sun, Yingying Tang, Kelvin O. Lim, Jijun Wang, Shanbao Tong, Hui Li, and Bin He, Abnormal dynamics of EEG oscillations in schizophrenia patients on multiple time scales, IEEE Transactions on Biomedical Engineering, 61(6): 1756-1764, 2014. 

16. Junfeng Sun, Xiangfei Hong, and Shanbao Tong, “Phase synchronization analysis of EEG signals: An evaluation based on surrogate tests”, IEEE Transactions on Biomedical Engineering, 59(8): 2254-2263, 2012.  

17. Junfeng Sun* and Michael Small, “Unified framework for detecting phase synchronization in coupled time series”, Physical Review E, 80: 046219, 2009.