Email : zhangshiyi@sjtu.edu.cn

Office address : 442 Wenxuan Bldg. (Minhang)


Shiyi Zhang has been an assistant professor in the School of Biomedical Engineering at the Shanghai Jiao Tong University since 2016. He obtained his bachelor’s degree from Peking University in Beijing in 2008. After then, he started his Ph.D. study with Prof. Karen Wooley at the Washington University in St. Louis. His PhD research interests ranged from degradable polymer for nanomedicine to the polymer self-assembly for functional nanostructures. Upon the completion of his PhD research in 2013, he arrived at MIT as a Max-Planck Postdoctoral Fellow with Prof. Robert S. Langer, focusing the translational study for gastrointestinal drug delivery. Zhang’s research appears in more than thirty articles in leading chemistry and polymer journals, including Nature Materials, Science Translational Medicine, Science Advances, Nature Communications, Journal of the American Chemical Society, ACS Nano, Advanced Materials, Advanced Functional Materials, Macromolecules and ACS Macro Letters, and results eight US and international patents. He also helped to build the biotech startup, Lyndra, to push the gastric retentive drug delivery system into Phase II clinical trial. He is the scientific founder of OnQuality Pharmaceuticals, a clinical stage biotech to develop innovative drugs and novel drug delivery systems that improve the quality of cancer patients’ lives. Dr. Zhang received 1000 Plan Program for Young Talents in 2015. His current research interests include: treatments for adverse effects caused by anti-cancer therapies and polymeric drugs for metabolic diseases. 

Education background

2004-2008 Bachelor - Peking University

2008-20013 Ph.D. – Washington University in St. Louis  

Work Experience

2013-2016, Postdoctoral fellow, Koch Institute, MIT

2016-now, Assistant professor, School of Biomedical Engineering, Shanghai Jiao Tong University

Areas of Research Interests

Treatments for adverse effects caused by anti-cancer therapies

Polymeric drugs for metabolic diseases.

Boards, Advisory Committees, Professional Organizations

• 1000Plan Program for Young Talents, 2015

• DSM Science & Technology Award USA Finalist, ACS Division of Polymer Chemistry, 2014

• AkzoNobel Student Award Finalist, ACS Division of Polymeric Materials: Science and Engineering, 2013

• DSM Science & Technology Award USA Finalist, ACS Division of Polymer Chemistry, 2013

• Max-Planck Postdoctoral Fellowship, MIT, 2013 - 2016

• Excellence in Graduate Polymer Research, ACS Division of Polymer Chemistry, 2013

• Chinese Government Scholarship for Outstanding Self-financed Students Studying Abroad, China Scholarship Council of Ministry of Education of China, 2012

• Awarded Research Fellowship from President Foundation, Peking University, 2006

• Special Fellowship award, Peking University, 2005

• Gold Medal, National High School Chemistry Olympiad, 2004 China Chemistry Olympiad Finalist (Top 24), China, 2004


Introduction to Translational Medicine and Career Development (Aut)

Selected Publications

(1) Sci. Adv. 2021,

(2) Sci. Transl. Med. 2016, 8, 365ra157.

(3) Nat. Mater., 2015, 14, 1065.

(4) Sci. Rep., 2013, 3, 3313.

(5) Adv. Mater., 2013, 25, 5609.

(6) Macromolecules, 2013, 46, 5141.

(7) Chem. Sci., 2013, 4, 2122.

(8) Adv. Funct. Mater., 2013, 23, 1767.

(9) J. Am. Chem. Soc., 2012, 134, 18467.

(10) J. Am. Chem. Soc., 2011, 133, 11046.