Dr. Ping Song is the Associate Professor of the Department of Biomedical Engineering at Shanghai Jiao Tong University. Dr. Song received her Ph.D. degree from Shanghai Institute of Applied Physics in Chinese academy of sciences. Then Dr. Song worked in Rice University as a postdoctoral researcher for one year and then was promoted to be a senior research scientist for four years. At the same time, Dr. Song part-time worked in NuProbe Inc as a senior research scientist and took charge in multiple projects. Dr. Song’s interesting research areas including: 1) cancer diagnosis and monitoring using PCR/qPCR/next generation sequencing/third generation sequencing; 2) early cancer detection based on biosensors; 3) DNA data storage. She has published many papers in top journals like Nature Biomedical Engineering, Nature Communications, Nature Protocols, Cancer Discovery, Nano Letters et al. In addition, Dr. Song focuses on commercialization of scientific and research findings. She has many Chinese patents, American patents, and international patents and some of the patents were licensed to company to be developed as kits.     

2006 – 2010 Bachelor - Yantai University

2010 – 2013 Master - Shanghai Normal University

2013 – 2016 Ph.D. – Shanghai Institute of Applied Physics, Chinese Academy of Sciences

2016 – 2017, Postdoc, Department of Biomedical Engineering, Rice University

2017 – 2021, Senior Research Scientist, Department of Biomedical Engineering, Rice University

2019 – 2021, Senior Research Scientist (part-time), NuProbe Inc

1) Cancer diagnosis and monitoring using PCR/qPCR/Next Generation Sequencing/Third Generation Sequencing;

2) Early cancer detection based on biosensors;

3) DNA data storage.

1. Ping Song, Sherry X. Chen … David Yu Zhang*, Detection and quantitation of low fraction DNA variants via low-depth sequencing using multiplexed allele enrichment, Nature Biomedical Engineering, 2021, 5, 690-701.

2. Ping Song¹, Lucia R. Wu¹ … David Yu Zhang*, The Biological and Biochemical Foundations of Non-invasive Cancer Diagnostics based on Cell-Free DNA, Nature Biomedical Engineering, (Accepted, Reference Number NBME-19-1360B).

3. Ping Song¹, Juwen Shen¹, Dekai Ye¹, Baijun Dong¹… Xiaolei Zuo*, Chunhai Fan*, Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework, Nature Communications, 2020, 11, 838.

4. Dekai Ye¹, Min Li¹, Tingting Zhai¹, Ping Song¹…Xiaolei Zuo*, Chunhai Fan*, Encapsulating living tumor cells with hybridization chain reaction". Nature Protocols, 2020, 15(7), 2163-2185.

5. Meihua Lin, Ping Song, Guobao Zhou, Xiaolei Zuo*, Chunhai Fan*, Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform, Nature Protocols, 2016, 11(7), 1244-1263.

6. Gabriele Romano, Pei-Ling Chen, Ping Song, … David Y Zhang, Jennifer A Wargo, Lawrence N Kwong*, A preexisting rare PIK3CAE545K subpopulation confers clinical resistance to MEK plus CDK4/6 inhibition in NRAS melanoma and is dependent on S6K1 signaling, Cancer Discovery, 2018, 8, 556-567.

7. Deepak Thirunavukarasu, Lauren Y Cheng, Ping Song, …David Yu Zhang*, Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection, Genome Biology, 2021, 22, 1-17.

8. Ping Song¹, Dekai Ye¹…. Chunhai Fan*, Xiaolei Zuo*, DNA hydrogel with aptamer-toehold-based recognition, cloaking, and decloaking of circulating tumor cells for live cell analysis, Nano Letters, 2017, 17(9), 5193-5198.

9. Ping Song …Chunhai Fan, Xiaolei Zuo*. Dynamic Modulation of DNA Hybridization Using Allosteric DNA Tetrahedral Nanostructures, Analytical Chemistry, 2016, 88, 8043-8049. 

10. Dan Zhu¹, Ping Song¹ …Chunhai Fan*, Hao Pei*. PolyA-Mediated DNA Assembly on Gold Nanoparticles for Thermodynamically Favorable and Rapid Hybridization Analysis, Analytical Chemistry, 2016, 88, 4949-4954.