People/Faculty
Faculty

Daixin DING

Associate professor

Email : ding_daixin@sjtu.edu.cn

Office address : Room 123, Med-X institute, Shanghai Jiao Tong University, No. 1954 Huashan Road, Xuhui District, Shanghai, China

Biography

As Tenure-Track Associate Professor at Shanghai Jiao Tong University, I earned my Ph.D. from the University of Galway, Ireland, in August 2023, under the supervision of Prof. William Wijns, former President of the European Association of Percutaneous Cardiovascular Interventions. That same year brought me back to China for postdoctoral research at Renji Hospital, Shanghai Jiao Tong University School of Medicine, before joining School of Biomedical Engineering as a faculty member in 2026.

My research centers on the technological development and clinical translation of cardiovascular computational functional assessment, with work published in leading international cardiovascular journals, including Nature Reviews Cardiology, European Heart Journal, JACC: Cardiovascular Interventions, and EuroIntervention. To date, I have published 50 journal articles, 15 as first or co-first author, and have contributed to 4 leading clinical textbooks or consensus documents.

I have led several major clinical validations of µFR, the first computational functional assessment technique based on single-view angiography, and further revealed the clinical value of coronary computational physiology in evaluating and predicting procedural results, setting new standards for assessing the immediate success of coronary interventions. Beyond epicardial coronary arteries, I am now also working on the diagnosis and phenotyping of downstream microvascular dysfunction based on coronary imaging.

I have been supported by the Ministry of Education Postdoctoral Overseas Talent Recruitment Program and the Shanghai Super Postdoctoral Program, and have served as Principal Investigator on projects including the NSFC Youth Science Fund Project (Category C), the Shanghai Baiyulan Talent Program Pujiang Project, and the General Program of the China Postdoctoral Science Foundation.

Education background
2020.09 – 2023.08 PhD University of Galway Medine
2017.09 – 2020.03 Master of Engineering Shanghai Jiao Tong University Biomedical Engineering
2013.09 – 2017.06 Bachelor of Engineering Huazhong University of Science and Technology Biomedical Engineering

 

Work Experience
2026.10 – Present Tenure-track Associated Prof School of Biomedical Engineering, Shanghai Jiao Tong University
2023.10 – 2026.09 Post-doc Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Areas of Research Interests

coronary hemodynamics; quantitative assessment of cardiovascular imaging; evaluation of percutaneous coronary intervention efficacy; precision diagnosis and phenotyping of coronary microvascular disease

Research Projects

1. National Natural Science Foundation of China, Youth Science Fund Project (Category C), 82502494, "Multi-scale coronary hemodynamic modeling for the evaluation of coronary arteries with combined epicardial stenosis and microvascular dysfunction," 2026.01 – 2028.12, Principal Investigator.

2. Shanghai Baiyulan Talent Program, Pujiang Project (Category D), 24PJD059, "Key mechanisms underlying hemodynamic interactions between epicardial coronary artery stenosis and coronary microvascular disease," 2024.12 – 2026.11, Principal Investigator.

3. China Postdoctoral Science Foundation, 75th Batch General Funding, 2024M752017, "Coronary angiography-based computational functional assessment in revascularization decision-making and prognosis evaluation," 2024.07 – 2026.09, Principal Investigator.

Selected Publications
  1. Ding D#, Wang X#, Li G#, Weng T, Pan M, Yang X, He R, Guan S, Qu X, Li M*, Wijns W, Tu S*. Impact of plaque eccentricity on the diagnostic performance of Murray-law based quantitative flow ratio computed from a single angiographic view. Catheter Cardiovasc Interv 2026;108:163-173.
  2. Li C#, Ding D#, Wang Z, He Y, Dong Y, Yang J, Shen Z, Pan D, Wijns W, Ge J*, Tu S*. Stepwise assessment of computational coronary physiology and plaque vulnerability: impact on coronary revascularization decision making. JACC Asia 2026;6(2):144-157.
  3. Ding D#, Zhang J#, Wu P, Wang Z, Shi H, Yu W, Hu X, Kang J, Hahn JY, Nam CW, Doh JH, Lee BK, Kim W, Huang J, Jiang F, Zhou H, Chen P, Tang L, Jiang W, Chen X, He W, Ahn SG, Yoon MH, Kim U, Ki YJ, Shin ES, Tahk SJ, Pu J, Wijns W, Wang J, Koo BK*, Tu S*. Prognostic value of postpercutaneous coronary intervention Murray-law-based quantitative flow ratio: post hoc analysis from FLAVOUR trial. JACC Asia 2025;5(1):59-70.
  4. Hwang HY#*, Ding D#, Kang J, Sun P, Sohn SH, Tu S*, Koo BK. Association between angiography-derived Murray law–based quantitative flow ratio and 1-year coronary artery bypass graft patency. JACC Cardiovasc Intv 2025;18(19):2326-2334.
  5. Fezzi S#, Ding D#, Mahfoud F, Huang J, Lansky AJ, Tu S*, Wijns W*. Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention? Nat Rev Cardiol 2024;21(9):652-662.
  6. Weng T#, Ding D#, Li G, Guan S, Han W, Gan Q, Li M, Qi L, Li C, Chen Y, Zhang L, Li T, Chen Y, Wijns W, Qu X*, Tu S*. Accuracy of coronary computed tomography angiography-derived quantitative flow ratio for onsite assessment of coronary lesions. EuroIntervention 2024;20(20):e1288-e1297.
  7. Aurigemma C#, Ding D#, Tu S, Li C, Yu W, Li Y, Leone AM, Romagnoli E, Vergallo R, Maino A, Trani C, Wijns W*, Burzotta F*. Three-year clinical impact of Murray law-based quantitative flow ratio and OCT- or FFR-guidance in angiographically intermediate coronary lesions. Circ Cardiovasc Interv 2024;17(5):e013191.
  8. Ding D, Tu S*, Li Y, Li C, Yu W, Liu X, Leone AM, Aurigemma C, Romagnoli E, Vergallo R, Trani C, Wijns W, Burzotta F. Quantitative flow ratio modulated by intracoronary optical coherence tomography for predicting physiological efficacy of percutaneous coronary intervention. Catheter Cardiovasc Interv 2023;102(1):36-45.
  9. Hu F#, Ding D#, Westra J, Li Y, Yu W, Wang Z, Kubo T, Chico JLG, Chen Y, Wijns W, Tu S*. Diagnostic accuracy of optical flow ratio: an individual patient-data meta-analysis. EuroIntervention 2023;19(2):e145-e154.
  10. Andersen BK#, Ding D#, Mogensen LJH, Tu S, Holm NR, Westra J*, Wijns W. Predictive value of post-percutaneous coronary intervention fractional flow reserve: a systematic review and meta-analysis. Eur Heart J Qual Care Clin Outcomes 2023;9(2):99-108.
  11. Ding D, Tu S*, Chang Y, Li C, Xu B*, Wijns W. Quantitative flow ratio based on Murray fractal law: accuracy of single versus two angiographic views. J Soc Cardiovasc Angiogr Interv 2022;1(5):100399.
  12. Ding D#, Huang J#, Westra J, Cohen DJ, Chen Y, Andersen BK, Holm NR, Xu B, Tu S*, Wijns W*. Immediate post-procedural functional assessment of percutaneous coronary intervention: current evidence and future directions. Eur Heart J 2021;42(27):2695-2707.
  13. Ding D#, Yu W#, Tauzin H, De Maria GL, Wu P, Yang F, Kotronias RA, Terentes-Printzios D, Wolfrum M, Banning AP, Meneveau N, Wijns W, Tu S*. Optical flow ratio for assessing stenting result and physiological significance of residual disease. EuroIntervention 2021;17(12):e989-e998.