Qiuning Lin is an Associate Professor at the School of Biomedical Engineering, Shanghai Jiao Tong University. She received a doctoral degree in Applied Chemistry from East China University of Science and Technology (ECUST) in 2013. For more than 10 years, Dr Lin’s research has been focused on the area of polymer materials and their biomedical applications. She has developed a light-induced in situ and non-free radical crosslinking technology. The hydrogel prepared via this strategy exhibited excellent biocompatibility and variability and has shown potential as scaffold for the tissue regeneration. In addition, she has also developed a light-induced drug release technology in which the drug was released from the carrier only within tumor microenvironment and under light excitation, so that the cancer cells are selectively killed without damaging to the normal cells. Dr Lin’s research has received diverse attentions from both academia and industry. To data, she has published over 50 scientific papers including Adv. Mater., J. Am. Chem. Soc. and Angew. Chem. Int. Ed., applied over 10 Chinese and World patents, and has received project grants from National Natural Science Foundation of China and Shanghai government.

2007/9-2013/6 Ph.D. - East China University of Science and Technology

2003/9-2007/6 Bachelor - East China University of Science and Technology 

2020/5-Now, Associate Professor, School of Biomedical Engineering, Shanghai Jiao Tong University

2018/9-2020/4, Associate Professor, Department of Chemistry, East China University of Science and Technology

2016/7-2018/8, Assistant Professor, Department of Chemistry, East China University of Science and Technology

2015/6-2016/6, Visiting Scholar, Composite Materials & Engineering Center, Washington State University

2013/10-2015/5, Postdoc, Department of Chemistry, East China University of Science and Technology

Biomaterials including hydrogel, bioelastomer, and drug release. 

Young Talent Yang Fan Plan (2014)

“Shanghai Outstanding PhD Thesis” awards (2015)

Tissue Engineering

National Natural Science Foundation of China (Outstanding Youth Program), No. 22022506, PI

National Natural Science Foundation of China (General Program), No. 21774030, PI

National Natural Science Foundation of China (Youth Program), No. 51403061, PI

Young Talent Yang Fan Plan, No. 14YF1404700, PI

National Natural Science Foundation of China for Postdoc, No. 2014M550221 and 2015T80405, PI

1. Q.-N. Lin#, L.-P. Yang#, Z.-Q. Wang, Y.-J. Hua, D.-S. Zhang, B.-K. Bao, C.-Y. Bao, X.-Q. Gong, L.-Y. Zhu*, Coumarin Photocages Modified with an Electron-Rich Styryl Moiety at the 3-Position: Long Wavelength Excitation, Rapid Photolysis and Photobleaching, Angew. Chem. Int. Ed., 2018, 57, 3722-3726. (IF=12.3)

2. Y.-L. Yang#, J.-Y. Zhang#, Z.-Z. Liu, Q.-N. Lin*, X.-L. Liu, C.-Y. Bao, Y. Wang*, L.-Y. Zhu*, Tissue-Integratable and Biocompatible Photogelation by the Imine Crosslinking Reaction, Adv. Mater., 2016, 28, 2724-2730. (IF=25.8)

3. Z.-Z. Liu, T. Liu, Q.-N. Lin*, C.-Y. Bao, L.-Y. Zhu*, Sequential Control over Thiol Click Chemistry by a Reversibly Photoactivated Thiol Mechanism of Spirothiopyran, Angew. Chem. Int. Ed., 2015, 54, 174-178. (IF=12.3)

4. Q.-N. Lin, C.-Y. Bao, Y.-L. Yang, Q.-N. Liang, D.-S. Zhang, S.-Y. Cheng, L.-Y. Zhu*, Highly Discriminating Photorelease of Anticancer Drugs Based on Tumor-Hypoxia Activatable Phototriggers Conjugated Chitosan Nanoparticles, Adv. Mater., 2013, 25, 1981-1986. (IF=25.8)

5. Q.-N. Lin, C.-Y. Bao, S.-Y. Cheng, Y.-L. Yang, W. Ji, L.-Y. Zhu*, Target-Activated Coumarin Phototriggers Specifically Switch on Fluorescence and Photocleavage upon Bonding to Thiol-Bearing Protein, J. Am. Chem. Soc., 2012, 134, 5052-5055. (IF=14.7)

6. Q.-N. Lin, Q. Huang, C.-Y. Li, C.-Y. Bao*, Z.-Z. Liu, F.-Y. Li, L.-Y. Zhu*, Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process, J. Am. Chem. Soc., 2010, 132, 10645-10647. (IF=14.7)

7. X.-L. Liu#, Y.-L. Yang#, Y. Li, X. Niu, B.-Z. Zhao, Y. Wang*, C.-Y. Bao, Z.-P. Xie, Q.-N. Lin*, L.-Y. Zhu, Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration, Nanoscale, 2017, 9, 4430-4438. (IF=7.0)

8. Y.-L. Yang#, X.-L. Liu#, Y. Li, Y. Wang*, C.-Y. Bao, Y.-F. Chen, Q.-N. Lin*, L. Zhu, A postoperative anti-adhesion barrier based on photoinduced imine-crosslinking hydrogel with tissue-adhesive ability, Acta Biomaterialia, 2017, 62, 199-209. (IF=6.6)

10. Z.-M. Du, N.-F. Li, Y.-J. Hua, Y. Shi, C.-Y. Bao, H.-B. Zhang, Y. Yang, Q.-N. Lin*, L.-Y. Zhu, Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran, Chem. Commun., 2017, 53, 13023-13026. (IF=6.2)

11. Y.-J. Hua#, Y. Gan#, Y.-Q. Zhang, B. Ouyang, B. Tu, C.-M. Zhang, X.-P. Zhong, C.-Y Bao, Y. Yang, Q.-N. Lin*, Q. Zhou, L.-Y. Zhu, Adaptable to Mechanically Stable Hydrogels Based on the Dynamic Covalent Cross-Linking of Thiol-Aldehyde Addition, ACS Macro Lett., 2019, 8, 310-314. (IF=5.8)

12. Y.-L. Yang, Y. Li, Q.-N. Lin*, C.-Y. Bao, L.-Y. Zhu*, In Situ Phototriggered Disulfide-Cross-Link Nanoparticles for Drug Delivery, ACS Macro Lett., 2016, 5, 301-305. (IF=5.8)

1. Qiuning Lin; Linyong Zhu; Yujie Hua; Yiqing Zhang; Chunyan Bao; Xuepeng Zhong; Photo induced crosslinking of hydrogel based on nitroso group and its preparation method and application, 2017, Chinese Patent, 201711132465.2.

2. Qiuning Lin; Yujie Hua; Linyong Zhu; Yiqing Zhang; Chunyan Bao; Xuepeng Zhong; Crosslinking of hydrogel based on thiol-aldehyde reaction and its preparation method and application, 2018, Chinese Patent, 201810108067.5.

3. Qiuning Lin; Jiangjiang Song; Chunyan Bao; Linyong Zhu; A light activated fluorescent probe with protein labeling function and its preparation method and application, 2015, Chinese Patent, CN201510161285.1.

4. Linyong Zhu; Yujie Hua; Qiuning Lin; Yiqing Zhang; Chunyan Bao; Xuepeng Zhong; A photo-cross linkable hydrogel material and its preparation method, raw material, product and application, 2017, Chinese Patent, 201711132951.4.

5. Linyong Zhu; Yujie Hua; Qiuning Lin; Yiqing Zhang; Chunyan Bao; Xuepeng Zhong; Photo-coupled synergistically crosslinked hydrogel material and its composition, preparation method, use, product, and preparation kit, 2017, Chinese Patent, 201711132472.2.

6. Hong Wang; Linyong Zhu; Qiuning Lin; Yang Wang; Photosensitive platelet-rich plasma gel and its preparation method and application, 2016, Chinese Patent, CN201611216812.5.